The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2007
Filed:
Jul. 06, 2004
James G. Mcarthur, San Carlos, CA (US);
Dale John Talbot, San Francisco, CA (US);
Andrew D. Simmons, San Mateo, CA (US);
Ryan Mcguinness, Oakland, CA (US);
Michael Kelly, Carlsbad, CA (US);
Lisa V. Tsui, Mountain View, CA (US);
Thomas Dull, San Francisco, CA (US);
James G. McArthur, San Carlos, CA (US);
Dale John Talbot, San Francisco, CA (US);
Andrew D. Simmons, San Mateo, CA (US);
Ryan McGuinness, Oakland, CA (US);
Michael Kelly, Carlsbad, CA (US);
Lisa V. Tsui, Mountain View, CA (US);
Thomas Dull, San Francisco, CA (US);
Cell Genesys, Inc, South San Francisco, CA (US);
Abstract
Recombinant lentiviruses and transfer vectors for transgene delivery as well as methods for gene therapy using such vectors are disclosed. The invention provides a third generation lentiviral packaging system and a set of vectors for producing recombinant lentiviruses, as well as novel tissue specific enhancer and promoter elements useful for optimizing liver specific transgene delivery. The transgene is preferably a blood clotting factor such as human factor IX (hFIX) or human factor VIII (hFVIII) and can be used for treatment of hemophilia.