The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2007

Filed:

Sep. 24, 2003
Applicants:

Tadanori Mayumi, Ikeda-shi, Osaka, JP;

Yasuo Tsutsumi, Minoo-shi, Osaka, JP;

Shinsaku Nakagawa, Yao-shi, Osaka, JP;

Hakuo Ikegami, Okayama, JP;

Inventors:

Tadanori Mayumi, Ikeda-shi, Osaka, JP;

Yasuo Tsutsumi, Minoo-shi, Osaka, JP;

Shinsaku Nakagawa, Yao-shi, Osaka, JP;

Hakuo Ikegami, Okayama, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C01K 1/00 (2006.01); A61K 45/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a physiologically active complex which comprises a proteinaceous part with TNF activity and a high molecular part bound artificially to the N-terminus of the proteinaceous part. The proteinaceous part in the complex has the amino acid sequence of SEQ ID NO:2 where Xaa is a member selected from the group consisting of asparagine, alanine, arginine, serine, threonine, proline, methionine, and leucine; while the high molecular part in the complex is a homopolymer of polyethylene glycol, copolymer of polyethylene glycol, or a derivative thereof.


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