The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2007
Filed:
Aug. 01, 2000
Gerald J. Chader, Bethesda, MD (US);
Ignacio R. Rodriguez, Rockville, MD (US);
Joyce Tombran-tink, Derwood, MD (US);
Sofia Patricia Becerra, Bethesda, MD (US);
Fintan R. Steele, Washington, DC (US);
Lincoln V. Johnson, Pasadena, CA (US);
Gerald J. Chader, Bethesda, MD (US);
Ignacio R. Rodriguez, Rockville, MD (US);
Joyce Tombran-Tink, Derwood, MD (US);
Sofia Patricia Becerra, Bethesda, MD (US);
Fintan R. Steele, Washington, DC (US);
Lincoln V. Johnson, Pasadena, CA (US);
Abstract
Nucleic acids encoding the neurotrophic protein known as pigment epithelium derived factor (PEDF), a truncated version of PEDF referred to as rPEDF, and equivalent proteins, vectors comprising such nucleic acids, host cells into which such vectors have been introduced, recombinant methods for producing PEDF, rPEDF, and equivalent proteins, the rPEDF protein and equivalent proteins of rPEDF and PEDF-BP, -BX and BA, and the PEDF protein produced by recombinant methods. Effects and uses of these variants on 1) neuronal differentiation (neurotrophic effect) 2) neuron survival (neuronotrophic effect) and 3) glial inhibition (gliastatic effect) are described.