The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2007
Filed:
Jun. 02, 2000
Arun K. Roy, San Antonio, TX (US);
Yan Lavrovsky, Geneva, CH;
Rakesh K. Tyagi, New Delhi, IN;
Chung S. Song, San Antonio, TX (US);
Bandana Chatterjee, San Antonio, TX (US);
Shuo Chen, San Antonio, TX (US);
Arun K. Roy, San Antonio, TX (US);
Yan Lavrovsky, Geneva, CH;
Rakesh K. Tyagi, New Delhi, IN;
Chung S. Song, San Antonio, TX (US);
Bandana Chatterjee, San Antonio, TX (US);
Shuo Chen, San Antonio, TX (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Abstract
Highly specific hammerhead ribozymes are provided that human target estrogen receptor mRNA. These ribozymes, designated RZ1 through RZ7 provide predictable mRNA cleavage products. Methods for inhibiting estrogen-dependent tumor growth, such as that characteristic of breast cancer, are also provided employing these ribozymes. One or both of the ribozymes may be used together or separately with equal efficiency. The ribozymes possess a sequence region with a catalytic core that provides the attributed catalytic activity to these ribozymes.