The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2007
Filed:
Jun. 18, 1999
Jindrich Kopecek, Salt Lake City, UT (US);
Russell Stewart, Salt Lake City, UT (US);
Karin Caldwell, Salt Lake City, UT (US);
Chung Wang, Salt Lake City, UT (US);
Chih-hu Ho, Salt Lake City, UT (US);
Jindrich Kopecek, Salt Lake City, UT (US);
Russell Stewart, Salt Lake City, UT (US);
Karin Caldwell, Salt Lake City, UT (US);
Chung Wang, Salt Lake City, UT (US);
Chih-Hu Ho, Salt Lake City, UT (US);
University of Utah Research Foundation, Salt Lake City, UT (US);
Abstract
A stimuli-responsive, hybrid hydrogel wherein the bulk of the polymer is made up of relatively inexpensive water soluble polymer strands crosslinked by protein domains. The responsiveness of the gel is controlled or modulated by the protein component. The physical and biological properties of the hydrogel are determined by specifically designed or engineered protein domains. The crosslinking of the protein domains to the water soluble polymers is by means of non-covalent bonding such as chelation or coordination bonding, biotin-avidin bonding, protein—protein interaction and protein-ligand interaction, or by means of covalent bonding. Methods of making and using the polymer-protein hydrogels are disclosed in this application.