The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2007
Filed:
Aug. 26, 2002
Andrew John Smallridge, Victoria, AU;
Maurice Arthur Trewhella, Victoria, AU;
Kylie Anne Wilkinson, Victoria, AU;
Andrew John Smallridge, Victoria, AU;
Maurice Arthur Trewhella, Victoria, AU;
Kylie Anne Wilkinson, Victoria, AU;
Victoria University of Technology, Footscray, AU;
Polychip Pharmaceuticals Pty. Ltd., Toorak, AU;
Abstract
A method for the preparation of a compound of formula (VI): in which Ris an optionally substituted C1–C6 alkyl; Ris H, OH, an optionally substituted C1–C6 alkyl or an optionally substituted C1–C6 alkoxy; Ris an optionally substituted aryl, an optionally substituted aralkyl, or an optionally substituted alkyl; and Ris H or an optionally substituted C1–C6 alkyl; the method including the step of subjecting a ketone of formula (V) in which R, Rand Rare as defined above, to reductive amination with an amine of formula RNHin which Ris an optionally substituted alkyl, and a reductant to form the compound of formula (VI), wherein the reaction is conducted in the presence of a supercritical fluid or a liquefied gas.