The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2007

Filed:

Jan. 06, 2004
Applicants:

Mark Edward Bunnage, Sandwich, GB;

Keith Michael Devries, Groton, CT (US);

Laurence James Harris, Sandwich, GB;

Philip Charles Levett, Sandwich, GB;

John Paul Mathias, Sandwich, GB;

Joanna Teresa Negri, Groton, CT (US);

Stephen Derek Albert Street, Sandwich, GB;

Albert Shaw Wood, Sandwich, GB;

Inventors:

Mark Edward Bunnage, Sandwich, GB;

Keith Michael DeVries, Groton, CT (US);

Laurence James Harris, Sandwich, GB;

Philip Charles Levett, Sandwich, GB;

John Paul Mathias, Sandwich, GB;

Joanna Teresa Negri, Groton, CT (US);

Stephen Derek Albert Street, Sandwich, GB;

Albert Shaw Wood, Sandwich, GB;

Assignee:

Pfizer Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process for the preparation of Compounds of the formula (1): wherein R, R, Rand Rare as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3',5′-monophosphate phosphodiestbrase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).


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