The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2007
Filed:
Oct. 07, 2005
John C. Reed, Rancho Santa Fe, CA (US);
Xiao-kun Zhang, San Diego, CA (US);
Bin Guo, Fargo, ND (US);
Bingzhen Lin, La Jolla, CA (US);
Siva Kumar Kolluri, San Diego, CA (US);
John C. Reed, Rancho Santa Fe, CA (US);
Xiao-kun Zhang, San Diego, CA (US);
Bin Guo, Fargo, ND (US);
Bingzhen Lin, La Jolla, CA (US);
Siva Kumar Kolluri, San Diego, CA (US);
The Burnham Institute, La Jolla, CA (US);
Abstract
Compounds that modulate the function of anti-apoptotic proteins such as Bcl-2 and Bcl-Xare identified. These compounds have the ability to convert the activity of Bcl-2-family member proteins from anti-apoptotic to pro-apoptotic. Methods for inducing apoptosis are described, together with methods for identifying molecules that induce apoptosis through interaction with Bcl-2-family members.