The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2007

Filed:

Feb. 14, 2005
Applicants:

Jean-michel Lerestif, Yvetot, FR;

Jean-pierre Lecouve, Le Havre, FR;

Jean-claude Souvie, Le Havre, FR;

Daniel Brigot, Sainte-Marie-des-Champs, FR;

Stéphane Horvath, La-Chapelle-Saint-Mesmin, FR;

Marie-noëlle Auguste, Orleans, FR;

Gérard Damien, Meung-sur-Loire, FR;

Inventors:

Jean-Michel Lerestif, Yvetot, FR;

Jean-Pierre Lecouve, Le Havre, FR;

Jean-Claude Souvie, Le Havre, FR;

Daniel Brigot, Sainte-Marie-des-Champs, FR;

Stéphane Horvath, La-Chapelle-Saint-Mesmin, FR;

Marie-Noëlle Auguste, Orleans, FR;

Gérard Damien, Meung-sur-Loire, FR;

Assignee:

Les Laboratoires Servier, Courbevoie Cedex, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 223/16 (2006.01); C07D 405/06 (2006.01); A61K 31/55 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Process for the synthesis of ivabradine of formula (I): addition salts with a pharmaceutically acceptable acid and hydrates thereof. α crystalline form of ivabradine hydrochloride. Medicinal products containing the a crystalline form of ivabradine hydrochloride, which are useful as bradycardics.


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