The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7175750 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 13, 2007

Filed:

Nov. 05, 2002
Applicants:

Zhiyong Guo, State College, PA (US);

Zhaowei Liu, Port Matilda, PA (US);

Qingbo LI, State College, PA (US);

Inventors:

Zhiyong Guo, State College, PA (US);

Zhaowei Liu, Port Matilda, PA (US);

Qingbo Li, State College, PA (US);

Assignee:

SpectruMedix LLC, State College, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a method for determining the presence of a mutation in a first sample comprising first nucleotides. The reference sample comprising reference nucleotides. The first sample and a reference sample are subjected to electrophoresis in the presence of at least one intercalating dye. During electrophoresis the temperature of the first sample and the reference sample is changed by an amount sufficient to change an electrophoretic mobility of at least one of the first or reference nucleotides. Fluorescence intensity data are obtained. The fluorescence intensity data are indicative of the presence of the first and reference nucleotides. At least one of the first sample or reference samples comprises products resulting from a polymerase chain reaction (PCR), the products not having been desalted prior to electrophoresis.


Find Patent Forward Citations

Guo, Zhiyong. (2007). System and method for temperature gradient capillary electrophoresis (U.S. Patent No. 7175750). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7175750

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