The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2007
Filed:
Sep. 16, 2002
Curt Dale Haffner, Durham, NC (US);
Istvan Kaldor, Durham, NC (US);
Darryl Lynn Mcdougald, Durham, NC (US);
Aaron Bayne Miller, Durham, NC (US);
Curt Dale Haffner, Durham, NC (US);
Istvan Kaldor, Durham, NC (US);
Darryl Lynn McDougald, Durham, NC (US);
Aaron Bayne Miller, Durham, NC (US);
SmithKline Beecham Corporation, Philadelphia, PA (US);
Abstract
The present invention includes novel retinoid compounds that have selectivity as RXR agonists on one or more isoforms of RXR, currently, RXRα, RXRβ, or RXRγ. The present compounds, and pharmaceutical compositions incorporating these compounds, therefore, are effective in treating conditions mediated by RXRs. Among other physiological responses, the compounds of the present invention reduce blood glucose and maintain body weight, and, thus, are useful for the treatment of diabetes (NIDDIM) and obesity.