The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2007
Filed:
Jul. 28, 2005
Susumu Igarashi, Tsukuba, JP;
Ryo Naito, Tsukuba, JP;
Yoshinori Okamoto, Tsukuba, JP;
Noriyuki Kawano, Tsukuba, JP;
Issei Tsukamoto, Tsukuba, JP;
Ippei Sato, Tsukuba, JP;
Makoto Takeuchi, Tsukuba, JP;
Hiroyuki Kanoh, Itabashi-ku, JP;
Masato Kobori, Tsukuba, JP;
Susumu Igarashi, Tsukuba, JP;
Ryo Naito, Tsukuba, JP;
Yoshinori Okamoto, Tsukuba, JP;
Noriyuki Kawano, Tsukuba, JP;
Issei Tsukamoto, Tsukuba, JP;
Ippei Sato, Tsukuba, JP;
Makoto Takeuchi, Tsukuba, JP;
Hiroyuki Kanoh, Itabashi-ku, JP;
Masato Kobori, Tsukuba, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
As a result of an effort made by us for the purpose of developing a therapeutic agent having a bone formation-stimulating effect by promoting the functions of osteoblasts, the present inventors discovered that a certain nitrogen-containing heterocyclic compound exhibits a potent bone formation-stimulating effect on the osteoblast and thus can serve as an excellent prophylactic or therapeutic agent against a metabolic bone disease, whereby establishing the present invention. Thus, the present invention provides a 3,6-disubstituted 1,2,4-triazolo[4,3-b]pyridazine compound or a pharmaceutically acceptable salt thereof as well as a pharmaceutical composition comprising such a compound and a pharmaceutically acceptable carrier, especially a bone-forming agent.