The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2007
Filed:
Jun. 27, 2002
Applicants:
Paul Zev Zimmet, Toorak, AU;
Frank Man-woon NG, Kew, AU;
Inventors:
Paul Zev Zimmet, Toorak, AU;
Frank Man-Woon Ng, Kew, AU;
Assignees:
International Diabetes Institute, Caulfield South, AU;
Monash University, Clayton, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/07 (2006.01); A61K 38/08 (2006.01); C07K 5/103 (2006.01); C07K 7/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
A peptide of the formula (Xaa)-Xaa-His-Thr-Asp-(Xaa), wherein Xaa is any amino acid; Xaais a hydrophobic amino acid, preferably Gly or Val; n1 is 0–10; and n2 is 0–10; and use thereof in regulating in vivo blood glucose levels in a human or other mammal, particularly in the treatment of Type 2 diabetes in a human. Preferably, the peptide is a tetrapeptide selected from Gly-His-Thr-Asp and Val-His-Thr-Asp. These hypoglycaemic peptides are isolated from human urine and they also have been chemically synthesized.