The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2007
Filed:
Sep. 22, 2003
Daniel Benigni, Skaneateles, NY (US);
Robert Stankavage, Bridgeport, NY (US);
Shu-jen Chiang, Manlius, NY (US);
Hsing Hou, Manlius, NY (US);
Bruce Eagan, Fayetteville, NY (US);
Dennis Gu, Skokie, IL (US);
David Hou, Baldwinsville, NY (US);
Les Mintzmyer, Manlius, NY (US);
Thomas P. Tully, Middlesex, NJ (US);
Brian L. Davis, Milltown, NJ (US);
Ivan Hargro, Roselle, NJ (US);
Mark Mascari, East Syracuse, NY (US);
Gabriel Galvin, Manlius, NY (US);
Gregory Stein, Mallory, NY (US);
Cary W. Mcconlogue, Plainsboro, NJ (US);
Fahri T. Comezoglu, Kendall Park, NJ (US);
Daniel Benigni, Skaneateles, NY (US);
Robert Stankavage, Bridgeport, NY (US);
Shu-Jen Chiang, Manlius, NY (US);
Hsing Hou, Manlius, NY (US);
Bruce Eagan, Fayetteville, NY (US);
Dennis Gu, Skokie, IL (US);
David Hou, Baldwinsville, NY (US);
Les Mintzmyer, Manlius, NY (US);
Thomas P. Tully, Middlesex, NJ (US);
Brian L. Davis, Milltown, NJ (US);
Ivan Hargro, Roselle, NJ (US);
Mark Mascari, East Syracuse, NY (US);
Gabriel Galvin, Manlius, NY (US);
Gregory Stein, Mallory, NY (US);
Cary W. McConlogue, Plainsboro, NJ (US);
Fahri T. Comezoglu, Kendall Park, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention relates to improved methods for the production, isolation and purification of epothilone B. These methods include, for example, a fermentation process for the production of epothilone B, isolation via adsorption onto a resin, and subsequent purification.