The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2007
Filed:
May. 04, 2005
Michael J. Gale, Jr., Dallas, TX (US);
Michael S. Brown, Dallas, TX (US);
Joseph L. Goldstein, Dallas, TX (US);
Chunfu Wang, Dallas, TX (US);
Jin YE, Dallas, TX (US);
Michael J. Gale, Jr., Dallas, TX (US);
Michael S. Brown, Dallas, TX (US);
Joseph L. Goldstein, Dallas, TX (US);
Chunfu Wang, Dallas, TX (US);
Jin Ye, Dallas, TX (US);
Board of Regents, The University of Texas System, Austin, TX (US);
Abstract
Agents that modulate an interaction of an FBL2 protein with an NS5A or NS5B Flaviviridae protein in a mixture are identified by contacting the mixture with a candidate agent under conditions wherein but for the presence of the agent, the FBL2 protein and the Flaviviridae protein engage in a reference interaction; and detecting an agent-biased interaction. Flaviviridae replication is inhibited by contacting a Flaviviridae-infected cell with an FBL2-specific reagent; and detecting a resultant Flaviviridae replication inhibition.