The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2007
Filed:
Jul. 22, 2003
Indolinone derivatives substituted in the 6-position, their preparation and their use as medicaments
Gerald Juergen Roth, Biberach, DE;
Armin Heckel, Biberach, DE;
Thorsten Lehmann-lintz, Ochsenhausen, DE;
Joerg Kley, Mittelbiberach, DE;
Frank Hilberg, Wien, AT;
Jacobus C. A. Van Meel, Moedling, AT;
Ulrike Tontsch-grunt, Baden, AT;
Gerald Juergen Roth, Biberach, DE;
Armin Heckel, Biberach, DE;
Thorsten Lehmann-Lintz, Ochsenhausen, DE;
Joerg Kley, Mittelbiberach, DE;
Frank Hilberg, Wien, AT;
Jacobus C. A. Van Meel, Moedling, AT;
Ulrike Tontsch-Grunt, Baden, AT;
Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, DE;
Abstract
The present invention relates to indolinone derivatives, substituted in the 6-position, of the formula in which Rto Rand X are as defined in claimto their tautomers, enantiomers, diastereomers, to their mixtures and to their salts, in particular their physiologically acceptable salts, which have useful pharmacological properties, in particular in inhibiting action on various receptor tyrosine kinases and on the proliferation of endothelial cells and various tumour cells, to medicaments comprising these compounds, to their use and to processes for their preparation.