The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2007
Filed:
Apr. 23, 2003
Gregory H. Merriman, Phillipsburg, NJ (US);
Philip M. Weintraub, Warren, NJ (US);
Jeffrey S. Sabol, Bridgewater, NJ (US);
Ramalinga M. Dharanipragada, Belle Mead, NJ (US);
Nicholas J. Hrib, Hillsborough, NJ (US);
John G. Jurcak, Bethlehem, PA (US);
Alexandre Gross, Jersey City, NJ (US);
Brian Whiteley, Lebanon, NJ (US);
Kwon Yon Musick, Raritan, NJ (US);
Joseph T. Klein, Neshanic Station, NJ (US);
Gregory H. Merriman, Phillipsburg, NJ (US);
Philip M. Weintraub, Warren, NJ (US);
Jeffrey S. Sabol, Bridgewater, NJ (US);
Ramalinga M. Dharanipragada, Belle Mead, NJ (US);
Nicholas J. Hrib, Hillsborough, NJ (US);
John G. Jurcak, Bethlehem, PA (US);
Alexandre Gross, Jersey City, NJ (US);
Brian Whiteley, Lebanon, NJ (US);
Kwon Yon Musick, Raritan, NJ (US);
Joseph T. Klein, Neshanic Station, NJ (US);
Aventis Pharmaceuticals Inc., Bridgewater, NJ (US);
Abstract
This invention discloses and claims a new class of indole derivatives for use in treating allergy, asthma, rhinitis, dermatitis, B-cell lymphomas, tumors and diseases associated with bacterial, rhinovirus or respiratory syncytial virus (RSV) infections. It has now been found that the compounds of this invention are capable of modulating T helper (Th) cells, Th1/Th2, and thereby capable of inhibiting the transcription of interleukin-4 (IL-4) message, IL-4 release or IL-4 production.