The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2007
Filed:
Dec. 20, 2002
Richard F. Schuman, Gaithersburg, MD (US);
John Fitzgerald Kokai-kun, Frederick, MD (US);
Simon J. Foster, Sheffield, GB;
Jeffrey R. Stinson, Brookeville, MD (US);
Gerald Walter Fischer, Bethesda, MD (US);
Richard F. Schuman, Gaithersburg, MD (US);
John Fitzgerald Kokai-Kun, Frederick, MD (US);
Simon J. Foster, Sheffield, GB;
Jeffrey R. Stinson, Brookeville, MD (US);
Gerald Walter Fischer, Bethesda, MD (US);
Biosynexus Incorporated, Gaithersburg, MD (US);
Abstract
The present invention encompasses protective monoclonal antibodies that bind to peptidoglycan of Gram-positive bacteria. The antibodies also bind to whole bacteria and enhance phagocytosis and killing of the bacteria in vitro and block nasal colonization by Gram-positive bacteria in vivo. The invention also provides human, humanized and chimeric antibodies. The invention also sets forth the heavy chain and light chain variable regions of an antibody within the invention.