The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2007

Filed:

Sep. 03, 2002
Applicants:

Manuel Baca, Ivanhoe, AU;

James A. Wells, Burlingame, CA (US);

Leonard G. Presta, San Francisco, CA (US);

Henry B. Lowman, El Granada, CA (US);

Yvonne Man-yee Chen, San Mateo, CA (US);

Inventors:

Manuel Baca, Ivanhoe, AU;

James A. Wells, Burlingame, CA (US);

Leonard G. Presta, San Francisco, CA (US);

Henry B. Lowman, El Granada, CA (US);

Yvonne Man-yee Chen, San Mateo, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo.


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