The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2007
Filed:
Dec. 05, 2001
Shanker Gupta, Rockville, MD (US);
Barry J. Maurer, Sylmar, CA (US);
C. Patrick Reynolds, Sherman Oaks, CA (US);
B. Rao Vishnuvajjala, Rockville, MD (US);
Shanker Gupta, Rockville, MD (US);
Barry J. Maurer, Sylmar, CA (US);
C. Patrick Reynolds, Sherman Oaks, CA (US);
B. Rao Vishnuvajjala, Rockville, MD (US);
Childrens Hospital Los Angeles, Los Angeles, CA (US);
Abstract
A pharmaceutical composition for parenteral delivery, comprising a retinide such as fenretinide in combination with a solvent capable of dispersing or solubilizing the retinide. The solvent comprises an alcohol, such as ethanol, in combination with an alkoxylated castor oil, such as CREMOPHOR® EL, or comprising a retinide, such as fenretinide, in an emulsion composed of a lipoid dispersed in an aqueous phase, a stabilizing amount of a non-ionic surfactant, optionally a solvent, and optionally an isotonic agent. In addition, a method of use in the treatment of hyperproliferative disorders, such as cancers is described.