The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2007

Filed:

Jul. 16, 2002
Applicants:

Qun Sun, Princeton, NJ (US);

Donald J. Kyle, Newtown, PA (US);

Parviz Gharagozloo, Pennington, NJ (US);

Ji Yang, Princeton Junction, NJ (US);

Inventors:

Qun Sun, Princeton, NJ (US);

Donald J. Kyle, Newtown, PA (US);

Parviz Gharagozloo, Pennington, NJ (US);

Ji Yang, Princeton Junction, NJ (US);

Assignee:

Euro-Celtique S.A., Luxembourg, LU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/14 (2006.01); C07D 417/06 (2006.01); A61K 31/426 (2006.01); A61K 31/4439 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates aryl substituted thiazolidinones of Formula I: or a pharmaceutically acceptable salt, or solvate thereof, wherein Rand R, are defined in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.


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