The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2007
Filed:
Feb. 19, 2004
Udo Hoss, Sherman Oaks, CA (US);
Hans-joerg Pfleiderer, Ulm, DE;
Ralf Gessler, Baienfurt, DE;
Hans-ulrich Zieten, Illerrieden, DE;
Rolf Fussgaenger, Blaustein-Weidach, DE;
Udo Hoss, Sherman Oaks, CA (US);
Hans-Joerg Pfleiderer, Ulm, DE;
Ralf Gessler, Baienfurt, DE;
Hans-Ulrich Zieten, Illerrieden, DE;
Rolf Fussgaenger, Blaustein-Weidach, DE;
Roche Diagnostics GmbH, Mannheim, DE;
Abstract
The invention concerns an arrangement for determining the concentration of glucose in a tissue fluid. In the microdialysis technology used for this purpose, perfusate-containing glucose is transported in intermittent delivery pulses through a microdialysis probe inserted into the tissue fluid and dialysate obtained in this process is passed to a measuring cell to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the tissue fluid by means of a control device in accordance with a command variable derived from the measurement signals of the measuring cell. When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the tissue fluid.