The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2007

Filed:

Apr. 01, 2005
Applicants:

Susumu Seino, Hyogo 659-0093, JP;

Takashi Miki, Hyogo, JP;

Toshihiko Iwanaga, Hokkaido, JP;

Masanari Matsumoto, Chiba, JP;

Inventors:

Susumu Seino, Hyogo 659-0093, JP;

Takashi Miki, Hyogo, JP;

Toshihiko Iwanaga, Hokkaido, JP;

Masanari Matsumoto, Chiba, JP;

Assignees:

JCR Pharmaceuticals Co., Ltd., Hyogo, JP;

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 67/00 (2006.01); G01K 33/00 (2006.01); C12N 5/08 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are a mouse homozygous or heterozygous for the defect of the Noc2 gene, and a tissue and a cell of the mouse. The Noc2 knockout mice, which exhibit stress-related insulin hyposecretion and accumulation of secretory granules of increased size and irregular shape in exocrine cells, provide a test system used in the development of therapeutic drugs for related disorders.


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