The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2007
Filed:
Jan. 23, 2003
Applicants:
David M. Chipman, Omer, IL;
Ze'ev Barak, Beer-Sheva, IL;
Stanislav Engel, Beer-Sheva, IL;
Maria Vyazmensky, Har Hebron, IL;
Inventors:
David M. Chipman, Omer, IL;
Ze'ev Barak, Beer-Sheva, IL;
Stanislav Engel, Beer-Sheva, IL;
Maria Vyazmensky, Har Hebron, IL;
Assignee:
Ben-Gurion University of the Negev, Beer-Sheva, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 45/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A biotransformation process for preparing chiral aromatic-hydroxy ketones in high yields is described, using 2-hydroxy-3-oxoacid synthase, such as AHAS or TSAS. Optionally substituted arylaldehydes and -oxoacids react in this process to provide pure enantiomers, useful as synthons in the production of various drugs, an example being (R)-phenylacetyl carbinol.