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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7166600 B1

PDFFull Text
Date of Patent:
Jan. 23, 2007

Filed:

Jan. 11, 2006

Thiocarbamate inhibitors of alpha-4 integrins

Applicant:

David Y. Jackson, San Bruno, CA (US);

Inventor:

David Y. Jackson, San Bruno, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:

David W Evans

Primary Examiner:

Joseph K McKane

Assistant Examiner:

Nyeemah Grazier

Int. Cl.
CPC ...
A61K 31/5375 (2006.01); A61K 31/4965 (2006.01); A61K 31/50 (2006.01); A61K 31/505 (2006.01); A61K 31/40 (2006.01); C07D 265/30 (2006.01); C07D 241/04 (2006.01); C07D 498/08 (2006.01); C07D 221/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides novel thiocarbamate alpha-4 inhibitors of the general formula (I) that are resistant to metabolism having improved half-life and/or clearance properties compared to corresponding carbamate compounds wherein substituents L, X, Y, Z, R–R, m, n, o and p are as defined herein. Also provided are compositions comprising compounds of formula I and a carrier, diluent or excipient as well as methods of treating a disease or condition mediated by the binding interaction of alpha-4 integrins to its ligands such as inflammatory diseases.

Find Patent Forward Citations

Jackson, David. (2007). Thiocarbamate inhibitors of alpha-4 integrins (U.S. Patent No. 7166600). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7166600

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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