The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2007
Filed:
Oct. 16, 2002
Alan M Fogelman, Beverly Hills, CA (US);
Gattadahalli M Anantharamaiah, Birmingham, CA (US);
Mohamad Navab, Los Angeles, CA (US);
Alan M Fogelman, Beverly Hills, CA (US);
Gattadahalli M Anantharamaiah, Birmingham, CA (US);
Mohamad Navab, Los Angeles, CA (US);
The Regents of the University of California, Oakland, CA (US);
The University of Alabama Research Foundation, Birmingham, AL (US);
Abstract
This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. The peptides are highly stable and readily administered via an oral route. In addition, the peptides inhibit osteoporosis. When administered with a statin, the peptides enhance the activity of the statin permitting the statin to be used at significantly lower dosages. In certain embodiments, the peptides range in length from about 10 up to about 30 amino acids, comprise at least one class A amphipathic helix, and protect a phospholipid against oxidation by an oxidizing agent.