The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2007

Filed:

Nov. 06, 2001
Applicants:

Makoto Sunagawa, Itami, JP;

Katsumi Kubota, New York, NY (US);

Masanori Itoh, Toyonaka, JP;

Erwin Goetschi, Reinach, CH;

Inventors:

Makoto Sunagawa, Itami, JP;

Katsumi Kubota, New York, NY (US);

Masanori Itoh, Toyonaka, JP;

Erwin Goetschi, Reinach, CH;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

1. A β-lactam compound of the formula [1]; wherein Ris a lower alkyl, a lower alkyl substituted by a hydroxy; Ris a hydrogen, a lower alkyl; X is O, S, NH; m and n are 0 to 4, Yis a halogen, cyano, a hydroxy, an amino, a lower alkyloxy, a lower alkylamino, a carboxy, a carbamoyl, a lower alkyl, etc., Yis hydrogen, an alkyl, cyano, —C(R)═NR(wherein Rand Rare hydrogen, an amino, an alkyl, etc., or Rand Rmay combine each other together with the nitrogen atom to form a 5- to 7-membered heterocyclic group), or a pharmaceutically acceptable salt thereof, or a non-toxic ester thereof, which has an excellent antibacterial activity against Gram-positive bacteria, especially against MRSA and MRCNS.


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