The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2007
Filed:
Aug. 05, 2003
Jean Rapin, Paris, FR;
Hans Klaus Witzmann, Egglkofen, DE;
Jean-marie Grumel, Tassin la Demi-Lune, FR;
Jacques Gonella, Muttenz, CH;
Jean Rapin, Paris, FR;
Hans Klaus Witzmann, Egglkofen, DE;
Jean-Marie Grumel, Tassin la Demi-Lune, FR;
Jacques Gonella, Muttenz, CH;
Neurotell AG, Hergiswil, CH;
Abstract
The invention relates to the use of specific tripeptides for the treatment of postlesional diseases of ischemic, traumatic or toxic origin. The tripeptide derivatives satisfy formula (I), wherein X represents OH, (C)alkoxy, NH, NH—C-alkyl, N(Calkyl); Ris a residue derived from any of the amino acids Phe, Tyr, Trp, Pro, each of which may optionally be substituted by a (C) alkoxy group, a (C) alkyl group or a halogen atom, and Ala, Val, Leu, or Ile; Ris a residue which is derived from any of the amino acids Gly, Ala, Ile, Val, Ser, Thr, His, Arg, Lys, Pro, Glu, Gln, pGlu, Asp, Leu and Asn; Rand Rindependently represent H, OH, (C1 –C5) alkyl, or (C)alkoxy, provided that Rand Rare not both OH or (C)alkoxy; Rrepresents H, OH, (C)alkyl or (C)alkoxy; and wherein Rpreferably represents a cinnamoyl residue; or pharmaceutically acceptable salts thereof.