The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2007
Filed:
May. 30, 2003
Yufen Zhao, Xiamen, Fujian 361005, CN;
Guo Tang, Xiamen, Fujian 361005, CN;
Ning Zhou, Xiamen, Fujian 361005, CN;
Liming HU, Xiamen, Fujian 361005, CN;
Yong Chen, Xiamen, Fujian 361005, CN;
Yufen Zhao, Xiamen, Fujian 361005, CN;
Guo Tang, Xiamen, Fujian 361005, CN;
Ning Zhou, Xiamen, Fujian 361005, CN;
Liming Hu, Xiamen, Fujian 361005, CN;
Yong Chen, Xiamen, Fujian 361005, CN;
Other;
Abstract
A synthesis method of alanyl-glutamine includes the steps of: The N-terminal protected alanine reacts with triphenylphosphine and hexachloroethane in organic solvent to form active ester, the active ester reacts with glutamine in a solution mixture containing organic solvent and aqueous solution of inorganic base, the resultant mixture is acidified with inorganic acid, and then the N-terminal protecting group is removed. In this method, the raw materials are cheap, the synthesis technique is simple, no disposals of separation and purification are needed, the product is easy to be separated and purified, the toxicities of all the reagents used in the course of production are minimal, it is advantageous to environment protection.