The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2007

Filed:

Aug. 26, 2004
Applicants:

Allan Svendsen, Birkeroed, DK;

Henrik Bisgaard-frantzen, Lyngby, DK;

Torben Borchert, Copenhagen N, DK;

Inventors:

Allan Svendsen, Birkeroed, DK;

Henrik Bisgaard-Frantzen, Lyngby, DK;

Torben Borchert, Copenhagen N, DK;

Assignee:

Novozymes A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/28 (2006.01); G01N 33/483 (2006.01); C07H 21/04 (2006.01); C12N 1/21 (2006.01); C12Q 1/40 (2006.01); G06F 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a method of constructing a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and at least one altered property as compared to the parent alpha-amylase, comprising i) analyzing the structure of the parent Termamyl-like alpha-amylase to identify at least one amino acid residue or at least one structural part of the Termamyl-like alpha-amylase structure, which amino acid residue or structural part is believed to be of relevance for altering the property of the parent Termamyl-like alpha-amylase (as evaluated on the basis of structural or functional considerations), ii) constructing a Termamyl-like alpha-amylase variant, which as compared to the parent Termamyl-like alpha-amylase, has been modified in the amino acid residue or structural part identified in i) so as to alter the property, and iii) testing the resulting Termamyl-like alpha-amylase variant for the property in question.


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