The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2007
Filed:
Jul. 08, 2004
Jeong-yoon Kim, Daejeon, KR;
Min-young Kim, Daejeon, KR;
Eun-kyu Park, Daejeon, KR;
Jae-young Chang, Daejeon, KR;
Hyun Ah Kang, Daejeon, KR;
Jeong-Yoon Kim, Daejeon, KR;
Min-Young Kim, Daejeon, KR;
Eun-Kyu Park, Daejeon, KR;
Jae-Young Chang, Daejeon, KR;
Hyun Ah Kang, Daejeon, KR;
Leadbio, Inc., Daejeon, KR;
Angiolab, Inc., Daejeon, KR;
Abstract
The present invention provides a human serum albumin-TIMP2 fusion protein having the amino acid sequence set forth in SEQ ID NO. 10, a polynucleotide encoding the same and a vector comprising the polynucleotide, a host cell transformed with the vector, a method for producing the human serum albumin-TIMP2 fusion protein and a pharmaceutical composition comprising the human serum albumin-TIMP2 fusion protein. The human serum albumin-TIMP2 fusion protein is stable and retains the activity of TIMP2, thus it can be used as a pharmaceutical composition to treat diseases related to angiogenesis and/or metastasis of cancer cells.