The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2007
Filed:
Jun. 07, 2002
Christian Hamon, Frankfurt am Main, DE;
Andrew Thompson, Cambridge, GB;
Thomas Neumann, Frankfurt am Main, DE;
Robert Johnstone, Bebington, GB;
Abdul Karim Abed Mohammed, Liverpool, GB;
Christian Hamon, Frankfurt am Main, DE;
Andrew Thompson, Cambridge, GB;
Thomas Neumann, Frankfurt am Main, DE;
Robert Johnstone, Bebington, GB;
Abdul Karim Abed Mohammed, Liverpool, GB;
Electrophoretics Limited, Surrey, GB;
Abstract
Provided is a method for characterizing a polypeptide, which method comprises the steps of: (a) optionally reducing cysteine disulphide bridges in the polypeptide to form free thiols, and capping the free thiols; (b) cleaving the polypeptide with a sequence specific cleavage reagent to form peptide fragments; (c) optionally deactivating the cleavage reagent; (d) capping one or more ε-amino groups that are present with a lysine reactive agent; (e) analyzing peptide fragments by mass spectrometry to form a mass fingerprint for the polypeptide; and (f) determining the identity of the polypeptide from the mass fingerprint.