The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2007
Filed:
Aug. 01, 2003
Methods of screening compositions for g protein-coupled receptor desensitization inhibitory activity
Robert H. Oakley, Durham, NC (US);
Lawrence S. Barak, Durham, NC (US);
Stephane A. Laporte, Outremont, CA;
Marc G. Caron, Hillsborough, NC (US);
Robert H. Oakley, Durham, NC (US);
Lawrence S. Barak, Durham, NC (US);
Stephane A. Laporte, Outremont, CA;
Marc G. Caron, Hillsborough, NC (US);
Molecular Devices Corporation, Sunnyvale, CA (US);
Abstract
The methods of the present invention allow the screening of a test composition for non-receptor-specific GPCR desensitization inhibitory activity. The methods involve screening a test composition for an indication of GPCR desensitization inhibitory activity against two or more GPCRs that are different from each other. When there is an indication that a particular test composition has GPCR desensitization inhibitory activity with respect to each of the two or more GPCRs that are different from one another, then, according to the present invention, there is an indication that the test composition has non-receptor-specific GPCR desensitization inhibitory activity.