The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2007
Filed:
Apr. 25, 2003
Jong Eun OH, Socho-ku, Seoul, 137-767, KR;
Keon Hyoung Lee, Mapo-ku, Seoul, 121-110, KR;
Tae Gwan Park, Yusong-ku, Taejon-si, 305-390, KR;
Yoon Sung Nam, Songpa-ku, Seoul, 138-789, KR;
Jong Eun Oh, Socho-ku, Seoul, 137-767, KR;
Keon Hyoung Lee, Mapo-ku, Seoul, 121-110, KR;
Tae Gwan Park, Yusong-ku, Taejon-si, 305-390, KR;
Yoon Sung Nam, Songpa-ku, Seoul, 138-789, KR;
Other;
Abstract
The present invention relates to the molecular sustained controlled release system constructed by the conjugation of molecules to be released with biodegradable polyester polymer via covalent bond and method for preparation thereof. In accordance with the present invention, the system may be formulated into microspheres, nanoparticles, or films. The molecular release rate from the above system can be regulated to be proportional to the chemical degradation rate of the biodegradable polyester polymers, resulting in near zero order kinetics profile of release without showing a burst effect. Moreover, the high loading efficiency of hydrophilic drugs can be achieved.