The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2007
Filed:
Aug. 20, 2003
Applicants:
Dennis C. Liotta, Stone Mountain, GA (US);
Raymond F. Schinazi, Decatur, GA (US);
Woo-baeg Choi, North Brunswick, NJ (US);
Inventors:
Dennis C. Liotta, Stone Mountain, GA (US);
Raymond F. Schinazi, Decatur, GA (US);
Woo-Baeg Choi, North Brunswick, NJ (US);
Assignee:
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/06 (2006.01); C07H 1/08 (2006.01); A01N 43/04 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the resolution of a racemic mixture of nucleoside enantiomers that includes the step of exposing the racemic mixture to an enzyme that preferentially catalyzes a reaction in one of the enantiomers. The nucleoside enantiomer (−)-2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner.