The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2007

Filed:

Dec. 03, 2003
Applicants:

Martin K. Safo, Richmond, VA (US);

Richmond Danso-danquah, Richmond, VA (US);

Samuel Nokuri, Richmond, VA (US);

Faik N. Musayev, Glen Allen, VA (US);

Gajanan S. Joshi, Glen Allen, VA (US);

James C. Burnett, Richmond, VA (US);

Donald J. Abraham, Midlothian, VA (US);

Inventors:

Martin K. Safo, Richmond, VA (US);

Richmond Danso-Danquah, Richmond, VA (US);

Samuel Nokuri, Richmond, VA (US);

Faik N. Musayev, Glen Allen, VA (US);

Gajanan S. Joshi, Glen Allen, VA (US);

James C. Burnett, Richmond, VA (US);

Donald J. Abraham, Midlothian, VA (US);

Assignee:

Xechem International, Inc., New Brunswick, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/341 (2006.01); A61K 31/381 (2006.01); A61K 31/427 (2006.01);
U.S. Cl.
CPC ...
Abstract

The provides compounds for the treatment of sickle-cell disease. In particular, the invention provides 5-membered heterocyclic anti-sickling agents that are highly effective and non-toxic, and methods for their use. The compounds include analogues and derivatives of naturally occurring occurring 5-hydroxymethyl-2-furfuraldehyde, 5-Ethyl-2-furfuraldehyde, 5-Methyl-2-furfuraldehyde, and 2-furfuraldehyde, and prodrug forms of the compound.


Find Patent Forward Citations

Loading…