The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2007

Filed:

Nov. 29, 2002
Applicants:

Andrew Faller, Windlesham, GB;

Peter Henry Milner, Harlow, GB;

John Gerard Ward, Harlow, GB;

Inventors:

Andrew Faller, Windlesham, GB;

Peter Henry Milner, Harlow, GB;

John Gerard Ward, Harlow, GB;

Assignee:

SmithKline Beecham p.l.c., Brentford, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/41 (2006.01); C07D 211/72 (2006.01); C07D 333/12 (2006.01); C07D 207/40 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase. BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.


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