The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2007
Filed:
May. 03, 2002
Arie Gutman, Haifa, IL;
Gennady Nisnevich, Haifa, IL;
Marina Etinger, Nesher, IL;
Igor Zaltzman, Haifa, IL;
Lev Yudovitch, Haifa, IL;
Boris Pertsikov, Nesher, IL;
Arie Gutman, Haifa, IL;
Gennady Nisnevich, Haifa, IL;
Marina Etinger, Nesher, IL;
Igor Zaltzman, Haifa, IL;
Lev Yudovitch, Haifa, IL;
Boris Pertsikov, Nesher, IL;
Finetech Laboratories Ltd., Haifa, IL;
Abstract
The present invention provides a new and effective process for the synthesis of 17-phenyl-18,19,20-trinor-PGFand its derivatives, including the anti-glaucoma drugs Bimatoprost and Latanoprost. The benefit of the present invention rises inter alia from the fact that a major intermediate involved in the synthesis of the above compounds may be isolated from a mixture containing also an undesired isomer, by crystallization. In addition, the undesired isomer may be oxidized to give the starting compound, which is then recycled.