The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2007

Filed:

Mar. 15, 2002
Applicants:

Zhaogen Chen, Noblesville, IN (US);

Michael Philip Cohen, Indianapolis, IN (US);

Matthew Joseph Fisher, Mooresville, IN (US);

Bruno Giethlen, Altorf, FR;

James Ronald Gillig, Indianapolis, IN (US);

Jefferson Ray Mccowan, Indianapolis, IN (US);

Shawn Christopher Miller, Morgantown, IN (US);

John Mehnert Schaus, Zionsville, IN (US);

Inventors:

Zhaogen Chen, Noblesville, IN (US);

Michael Philip Cohen, Indianapolis, IN (US);

Matthew Joseph Fisher, Mooresville, IN (US);

Bruno Giethlen, Altorf, FR;

James Ronald Gillig, Indianapolis, IN (US);

Jefferson Ray McCowan, Indianapolis, IN (US);

Shawn Christopher Miller, Morgantown, IN (US);

John Mehnert Schaus, Zionsville, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4045 (2006.01); A61K 31/137 (2006.01); C07D 209/14 (2006.01); C07C 211/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds of formula I pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are antagonists of the 5-HTreceptor. The present invention further provides a method of treating disorders associated with 5-HTreceptors, including schizophrenia, anxiety, Alzheimer's disease, and cognitive disorders selected from the group consisting of age-related cognitive decline, mild cognitive impairment, and dementia, comprising: administering to a patient in need thereof an effective amount of a compound of formula I.


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