The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2007

Filed:

Apr. 20, 2004
Applicants:

Anne Marie Smith, Glen Gardner, NJ (US);

Michael Cucolo, Basking Ridge, NJ (US);

Munir N. Nassar, Skillman, NJ (US);

Inventors:

Anne Marie Smith, Glen Gardner, NJ (US);

Michael Cucolo, Basking Ridge, NJ (US);

Munir N. Nassar, Skillman, NJ (US);

Assignee:

Bristol Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/724 (2006.01); A61K 31/715 (2006.01);
U.S. Cl.
CPC ...
Abstract

A ras-farnesyltransferase inhibitor complex formed from a ras-farnesyltransferase inhibitor or a pharmaceutically acceptable salt thereof, a substituted cyclodextrin, and ethanol is provided. The complex has unexpectedly high aqueous solubility of the ras-farnesyltransferase inhibitor, improved dissolution, enhanced stability and is essentially free of particulate matter.


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