The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2007
Filed:
Sep. 02, 2003
Manfred Watzele, Wellheim, DE;
Bernd Buchberger, Peissenberg, DE;
Hans Schels, Munich, DE;
Horst Menzler, Seeshaupt, DE;
Ulrike Fischer, Penzberg, DE;
Manfred Watzele, Wellheim, DE;
Bernd Buchberger, Peissenberg, DE;
Hans Schels, Munich, DE;
Horst Menzler, Seeshaupt, DE;
Ulrike Fischer, Penzberg, DE;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
The invention is a multichamber microdialysis device with a multitude of sample chambers in close side by side arrangement (similar to a microtiter plate) for receiving liquid samples, and at least one dialysate chamber for receiving a dialysate liquid. The sample chambers are surrounded by circumferential sidewalls and are in liquid exchange contact to a neighboring dialysis chamber via an exchange opening covered by a semipermeable membrane. The semipermeable membrane is fixed liquid-tight to the walls of the sample chamber, so that a diffusion exchange between the sample chamber and the correspondingly neighboring dialysate chamber is only possible via the membrane. Consequently, only molecules with a molecular weight below the molecular cut-off of the semipermeable membrane can diffuse from the sample chamber to the dialysate chamber or from the dialysate chamber to the sample chamber.