The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2006

Filed:

Aug. 06, 2003
Applicants:

Manfred Schudok, Eppstein/Ts., DE;

Otmar Klingler, Rodgau, DE;

Hans-peter Nestler, Kelkheim, DE;

Hans Matter, Langenselbold, DE;

Herman Schreuder, Hofheim-Lorsbach, DE;

Inventors:

Manfred Schudok, Eppstein/Ts., DE;

Otmar Klingler, Rodgau, DE;

Hans-Peter Nestler, Kelkheim, DE;

Hans Matter, Langenselbold, DE;

Herman Schreuder, Hofheim-Lorsbach, DE;

Assignee:

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;

Attorney:
Int. Cl.
CPC ...
C07D 213/75 (2006.01); A61K 31/44 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula I, in which R, R, A, and B having the definitions set forth in the claims, are valuable pharmacologically active compounds, which exhibit a strong antithrombotic effect and are suitable, for example, for treating thromboembolic diseases and restenoses. They are reversible inhibitors of the blood clotting enzyme factor VIIa and can in general be applied in conditions in which an undesired activity of factor VIIa is present or for the cure or prevention of which an inhibition of factor VIIa is intended. Also disclosed are processes for the preparation of compounds of formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.


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