The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2006

Filed:

Jan. 30, 2004
Applicants:

Dale S. Dhanoa, Wakefield, MA (US);

Dongli Chen, Chestnut Hill, MA (US);

Oren Becker, Mevaseret Zion, IL;

Silvia Noiman, Herzliya, IL;

Srinivasa Rao Cheruku, Woburn, MA (US);

Yael Marantz, Kadima, IL;

Anurag Sharadendu, Salem, NH (US);

Sharon Shachem, Alfey Menashe, IL;

Alexander Heifetz, IBeni-Brak, IL;

Pradyumna Mohanty, Woburn, MA (US);

Boaz Inbal, Kfar Shmuel, IL;

Merav Fichman, Modi'in, IL;

Raphael Nudelman, Rehovot, IL;

Shay Bar-haim, Netanya, IL;

Inventors:

Dale S. Dhanoa, Wakefield, MA (US);

Dongli Chen, Chestnut Hill, MA (US);

Oren Becker, Mevaseret Zion, IL;

Silvia Noiman, Herzliya, IL;

Srinivasa Rao Cheruku, Woburn, MA (US);

Yael Marantz, Kadima, IL;

Anurag Sharadendu, Salem, NH (US);

Sharon Shachem, Alfey Menashe, IL;

Alexander Heifetz, IBeni-Brak, IL;

Pradyumna Mohanty, Woburn, MA (US);

Boaz Inbal, Kfar Shmuel, IL;

Merav Fichman, Modi'in, IL;

Raphael Nudelman, Rehovot, IL;

Shay Bar-Haim, Netanya, IL;

Assignee:

Epix Delaware, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); A61K 31/496 (2006.01); C07D 295/13 (2006.01); C07D 401/06 (2006.01); A61K 31/506 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by Formulae I: and II, and synthesis and uses of those compounds for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.


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