The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2006

Filed:

Sep. 06, 2002
Applicants:

Kazuhiko Torisu, Mishima-gun, JP;

Tomoyuki Hasegawa, Sakai-gun, JP;

Kaoru Kobayashi, Mishima-gun, JP;

Fumio Nambu, Mishima-gun, JP;

Inventors:

Kazuhiko Torisu, Mishima-gun, JP;

Tomoyuki Hasegawa, Sakai-gun, JP;

Kaoru Kobayashi, Mishima-gun, JP;

Fumio Nambu, Mishima-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/538 (2006.01); A61K 31/404 (2006.01); C07D 265/36 (2006.01); C07D 209/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Indole derivatives represented by formula (I) wherein all symbols represent the same as that in specification), production methods thereof, and DP receptor antagonist comprising them as active ingredients. Since the compounds of formula (I) binds and antagonizes to DP receptor, they are useful for the prevention and/or treatment against allergic diseases, diseases accompanied with itching, secondary diseases generated by behaviors caused by itching, inflammation, chronic obstructive pulmonary disease, ischemic reperfusion disorder, cerebrovascular disorder, pleuritis complicated by rheumatoid arthritis, ulcerative colitis.


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