The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7153664 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 26, 2006

Filed:

May. 20, 2002
Applicant:

Kunihiro Matsumoto, 2-44, Taomo-cho, Showa-ku, Nagoya-shi, Aichi 466-0801, JP;

Inventor:

Kunihiro Matsumoto, 2-44, Taomo-cho, Showa-ku, Nagoya-shi, Aichi 466-0801, JP;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12P 21/06 (2006.01); C12N 15/74 (2006.01); C12N 5/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A novel signal transducer TAB2 which acts as an adapter molecule of TRAF6 and TAK1 and mediates the activation of TAK1 in the signal transduction of IL-1 was isolated. TAB2 induced the activation of NF-κB and JNK by IL-1. The signal transduction by IL-1 was inhibited by inhibiting the signal transduction of TAB2 with the use of a dominant negative mutant of TAB2. A compound inhibiting the signal transduction in TAB2 is useful as an anti-inflammatory drug.


Find Patent Forward Citations

Matsumoto, Kunihiro. (2006). Signal transduction protein tab2 (U.S. Patent No. 7153664). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7153664

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