The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2006

Filed:

Apr. 22, 2004
Applicants:

Jonathan Caudill, Ashville, OH (US);

Mark Cooney, Grove City, OH (US);

Satish C. Nigam, Hilliard, OH (US);

Inventors:

Jonathan Caudill, Ashville, OH (US);

Mark Cooney, Grove City, OH (US);

Satish C. Nigam, Hilliard, OH (US);

Assignee:

ISP Investments Inc., Wilmington, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 241/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for the preparation of pharmaceutically acceptable salts of 5-methylpyrazine-carboxylic acid-4-oxide by using the oxidizing agent OXONE® for the N-oxidation of Cmethylpyrazinecarboxylic acid esters. The pharmaceutically acceptable salts are then formed by the saponification of the esters followed by alcohol precipitation.


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