The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2006
Filed:
Jul. 11, 1995
Applicants:
Yasutaka Hoshino, Wheaton, MD (US);
Albert Z. Kapikian, Rockville, MD (US);
Robert M. Chanock, Bethesda, MD (US);
Inventors:
Yasutaka Hoshino, Wheaton, MD (US);
Albert Z. Kapikian, Rockville, MD (US);
Robert M. Chanock, Bethesda, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/04 (2006.01); C12N 7/08 (2006.01); A61K 39/15 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides vaccine compositions of attenuated human rotavirus. More particularly, the attenuated human rotavirus is produced by cold passage and thus contains attenuating mutations which produce virus having a cold-adapted (ca) and temperature sensitive (ts) phenotype. The attenuated strains are used in methods for stimulating the immune system of an individual to induce protection against human rotavirus by administration of the ca attenuated rotavirus.