The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2006
Filed:
Jan. 07, 2003
Thennati Rajamannar, Baroda, IN;
Kilaru Srinivasu, Baroda, IN;
Nileshkumar Sureshbhai Patel, Baroda, IN;
Chinnapillai Rajendran, Hyderabad, IN;
Thennati Rajamannar, Baroda, IN;
Kilaru Srinivasu, Baroda, IN;
Nileshkumar Sureshbhai Patel, Baroda, IN;
Chinnapillai Rajendran, Hyderabad, IN;
Sun Pharmaceutical Industries, Mumbai, IN;
Abstract
The present invention provides a process for the preparation of crude 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile base with substantially low levels of impurities by arresting the formation of substantial amount of carboxamide impurity, high molecular weight impurities and suppressing the formation of desmethylcitalopram besides taking the cyanide exchange reaction to near completion and thus avoiding an extensive and expensive purification process.