The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2006
Filed:
Dec. 19, 2002
Applicants:
Takashi Tsukamoto, Ellicott City, MD (US);
Brian Grella, Richmond, VA (US);
Pavel Majer, Sykesville, MD (US);
Inventors:
Takashi Tsukamoto, Ellicott City, MD (US);
Brian Grella, Richmond, VA (US);
Pavel Majer, Sykesville, MD (US);
Assignee:
Guilford Pharmaceuticals Inc., Baltimore, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); C07D 209/02 (2006.01); C07D 209/42 (2006.01); A61K 31/405 (2006.01); C07D 209/34 (2006.01); C07D 43/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALAdase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.