The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2006

Filed:

Jun. 01, 2004
Applicants:

Robert Hugh Bradbury, Macklesfield, GB;

Jason Grant Kettle, Macklesfield, GB;

James Mccabe, Macklesfield, GB;

Andrew Turner, Macklesfield, GB;

Laurent Francois Andre Hennequin, Reims, FR;

Inventors:

Robert Hugh Bradbury, Macklesfield, GB;

Jason Grant Kettle, Macklesfield, GB;

James McCabe, Macklesfield, GB;

Andrew Turner, Macklesfield, GB;

Laurent Francois Andre Hennequin, Reims, FR;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 43/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention concerns quinazoline derivatives of Formula I wherein Rand Rhave any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB, particularly EGF, receptor tyrosine kinases.


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